Article

Genetically Encoded and Modular SubCellular Organelle Probes (GEM-SCOPe) reveal lysosomal and mitochondrial dysfunction driven by <i>PRKN</i> knockout

2024-05-21

Abstract excerpt

<h4>Summary</h4> Cellular processes including lysosomal and mitochondrial dysfunction are implicated in the development of many diseases. Quantitative visualization of mitochondria and lysosomes is crucial to understand how these organelles are dysregulated during disease. To address a gap in live-imaging tools, we developed GEM-SCOPe (Genetically Encoded and Modular SubCellular Organelle Probes), a modular toolb...

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Literature Corpus work: a2645f98-7ab4-5246-b228-222290cf59a3
DOI: 10.1101/2024.05.21.594886

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Genetically Encoded and Modular SubCellular Organelle Probes (GEM-SCOPe) reveal lysosomal and mitochondrial dysfunction driven by <i>PRKN</i> knockoutDOI 10.1101/2024.05.21.594886Read

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