Article

dCas9 targeted proteome profiling reveals p300-mediated reciprocal regulation of SMAD and SP1 as a driver of GM2synthase transcription in renal cell carcinoma

2025-09-18

Abstract excerpt

Glycolipids constitute an important component of the plasma membrane based on both abundance as well as function. Gangliosides, being a class of structurally diverse and functionally varied glycolipids, can act both as a receptor as well as a ligand and therefore is established as a crucial player in several normal cellular processes. In certain diseases, and in particular cancer, select gangliosides are over-expr...

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Literature Corpus work: 5757e2db-1281-5766-b8ca-ed3a1ccccbc3
DOI: 10.1101/2025.09.16.676212

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dCas9 targeted proteome profiling reveals p300-mediated reciprocal regulation of SMAD and SP1 as a driver of GM2synthase transcription in renal cell carcinomaDOI 10.1101/2025.09.16.676212Read

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