Article

Multi-region brain transcriptomes uncover two subtypes of aging individuals with differences in Alzheimer risk and the impact of <i>APOEε4</i>

2023-01-25

Abstract excerpt

The heterogeneity of the older population suggests the existence of subsets of individuals which share certain brain molecular features and respond differently to risk factors for Alzheimer’s disease, but this population structure remains poorly defined. Here, we performed an unsupervised clustering of individuals with multi-region brain transcriptomes to assess whether a broader approach, simultaneously consideri...

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Literature Corpus work: 5745ac76-0b02-5bf2-8ecf-d1fd7755b158
DOI: 10.1101/2023.01.25.524961

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Multi-region brain transcriptomes uncover two subtypes of aging individuals with differences in Alzheimer risk and the impact of <i>APOEε4</i>DOI 10.1101/2023.01.25.524961Read

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