Article

Human brain aging heterogeneity observed from multi-region omics data reveals a subtype closely related to Alzheimer’s disease

2024-03-05

Abstract excerpt

INTRODUCTION: The interconnection between brain aging and Alzheimer’s disease (AD) remain to be elucidated. METHODS: We investigated multi-omics (transcriptomics and proteomics) data from multiple brain regions (i.e., the hippocampus (HIPP), prefrontal cortex (PFC), and cerebellum (CRBL)) in cognitively normal individuals. RESULTS: We found that brain samples could be divided into ADL (AD-like) and NL (normal) sub...

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Literature Corpus work: 21875ddd-6c8a-5b21-baf6-73ce26343647
DOI: 10.1101/2024.03.01.582970

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