Article

Strain-dependent impact of G and SH deletions provide new insights for live-attenuated HMPV vaccine development

2019-09-25

Abstract excerpt

Human metapneumovirus (HMPV) is a major pediatric respiratory pathogen with currently no specific treatment or licensed vaccine. Different strategies to prevent this infection have been evaluated, including live-attenuated vaccines (LAV) based on SH and/or G protein deletions. This approach showed promising outcomes but has not been evaluated further using different viral strains. In that regard, we previously sho...

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Literature Corpus work: 3cf0d431-5347-50bd-8677-d017bbe58d49
DOI: 10.1101/781302

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