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Metavac®-RSV mucosal bivalent vaccine candidate protects cotton rats against RSV and HMPV and its production process in serum-free Vero cells is scalable in a 2L bioreactor

2025-04-11

Abstract excerpt

<title>Abstract</title> <p>Respiratory Syncytial Virus (RSV) and Human Metapneumovirus (HMPV) are the main etiologic agents of viral bronchiolitis and pneumonia in children and elderly. As Live-Attenuated Vaccines (LAV) can stimulate robust mucosal and cellular responses, we previously engineered an HMPV-based bivalent LAV Metavac®-RSV and reported its capacity to protect mice against HMPV and RSV challenges afte...

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Literature Corpus work
68241ed8-9962-53cd-8028-327e033a1b47
DOI
10.21203/rs.3.rs-6217777/v1
Open publication

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Metavac®-RSV mucosal bivalent vaccine candidate protects cotton rats against RSV and HMPV and its production process in serum-free Vero cells is scalable in a 2L bioreactorDOI 10.21203/rs.3.rs-6217777/v1
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