Article
Live vaccines for human metapneumovirus designed by reverse genetics.
Expert review of vaccines - 1 Oct 2006
Buchholz Ursula J, Nagashima Kunio, Murphy Brian R, Collins Peter L
Abstract excerpt
Human metapneumovirus (HMPV) was first described in 2001 and has quickly become recognized as an important cause of respiratory tract disease worldwide, especially in the pediatric population. A vaccine against HMPV is required to prevent severe disease associated with infection in infancy. The primary strategy is to develop a live-attenuated virus for intranasal immunization, which is particularly well suited...
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