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Article

Analysis of case-control association studies with known risk variants.

Bioinformatics (Oxford, England) - 1 Jul 2012

Zaitlen Noah, Pasaniuc Bogdan, Patterson Nick, Pollack Samuela, Voight Benjamin, Groop Leif, Altshuler David, Henderson Brian E, Kolonel Laurence N, Le Marchand Loic, Waters Kevin, Haiman Christopher A, Stranger Barbara E, Dermitzakis Emmanouil T, Kraft Peter, Price Alkes L

Abstract excerpt

MOTIVATION: The question of how to best use information from known associated variants when conducting disease association studies has yet to be answered. Some studies compute a marginal P-value for each Several Nucleotide Polymorphisms independently, ignoring previously discovered variants. Othe...

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Identifiers

PMID: 22556366
DOI: 10.1093/bioinformatics/bts259
PMCID: PMC3381970

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-22556366-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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