Article

Generation of inheritable A-to-G transitions using adenine base editing and NG-PAM Cas9 in <i>Arabidopsis thaliana</i>

2022-06-07

Abstract excerpt

CRISPR/Cas9 technology is an important tool for functional genomics and crop improvement. It can be used to generate mutations at precise positions in the genome. Base editors consist of deaminase components and Cas9 to specify the type of mutation, such as C-to-T (cytosine base editors) or A-to-G (adenine base editors) transition. Available adenine base editor vectors usually make use of canonical Cas9, which lim...

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Literature Corpus work: 5704f439-a7da-59f2-8233-d002a88c8a6c
DOI: 10.1101/2022.06.07.495175

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