Article
Hemodynamic molecular imaging of tumor-associated enzyme activity in the living brain
2021-05-12
Abstract excerpt
<h4>ABSTRACT</h4> Molecular imaging could have great utility for detecting, classifying, and guiding treatment of brain disorders, but existing probes offer limited capability for assessing relevant physiological parameters. Here we describe a potent approach for noninvasive mapping of cancer-associated enzyme activity using a molecular sensor that acts on the vasculature, providing a diagnostic readout via local...
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Identifiers and source
- Literature Corpus work
- 56fe7a4f-b6b6-5d86-80ff-9d31f825716f
- DOI
- 10.1101/2021.05.11.443603
