Article

Simultaneous single cell measurements of intranuclear proteins and gene expression

2021-01-19

Abstract excerpt

Identifying gene regulatory targets of nuclear proteins in tissues remains a challenge. Here we describe in tranuclear C ellular I ndexing of T ranscriptomes and E pitopes (inCITE-seq), a scalable method for measuring multiplexed intranuclear protein levels and the transcriptome in parallel in thousands of cells, enabling joint analysis of TF levels and gene expression in vivo . We apply inCITE-seq to charac...

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Literature Corpus work: 82907456-7806-5cb4-935c-9c2f8c156c3b
DOI: 10.1101/2021.01.18.427139

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