Article

Aberrant expression of homing markers on dendritic cells drives inflammation in Crohn's disease

2016-01-01

Abstract excerpt

CD is a chronic transmural inflammatory disease of the gut. The aetiology of CD is unknown, but is likely to result from dysregulated innate immune responses to gut microbiota leading to over activation of the acquired immune system in a genetically susceptible host. Inflammation occurs anywhere from mouth to anus, in addition to extra-intestinal sites. This compartmentalisation of the inflammatory process is link...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 56a9d970-0ec9-5d44-bd09-90bf226571ac
DOI: 10.25560/31866

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Aberrant expression of homing markers on dendritic cells drives inflammation in Crohn's diseaseDOI 10.25560/31866Read

The immunomodulatory effects of vitamin D in Crohn's disease : dendritic cells, gamma delta T-cells and homingSemantic proximity Read

Increased Th17-inducing activity of CD14+ CD163 low myeloid cells in intestinal lamina propria of patients with Crohn's disease.Semantic proximity Read

Recent progress in understanding the phenotype and function of intestinal dendritic cells and macrophages.Semantic proximity Read

Profiling of Human Circulating Dendritic Cells and Monocyte Subsets Discriminates Between Type and Mucosal Status in Patients With Inflammatory Bowel Disease.Semantic proximity Read

Studies of the aetiopathogenesis of pouchitisSemantic proximity Read

Langerin-expressing dendritic cells in gut-associated lymphoid tissues.Semantic proximity Read

CD4+NKG2D+ T cells in Crohn's disease mediate inflammatory and cytotoxic responses through MICA interactions.Semantic proximity Read

Human gut-specific homeostatic dendritic cells are generated from blood precursors by the gut microenvironment.Semantic proximity Read

Polarized production of T-helper cell type 1 cells in Peyer's patches in Crohn's disease.Semantic proximity Read

Distribution of human colonic dendritic cells and macrophages--functional implications.Semantic proximity Read

Characterization of antigen-presenting dendritic cells in the peripheral blood and colonic mucosa of patients with ulcerative colitis.Semantic proximity Read

Regulation of the mucosal phenotype in dendritic cells by PPARγ: role of tissue microenvironment.Semantic proximity Read