Article

Studies of the aetiopathogenesis of pouchitis

2015-01-01

Abstract excerpt

The ileal pouch offers a unique opportunity to study the inter-relationships between the gut microbiota, barrier function and host immune responses. Intestinal dendritic cells (DC) are pivotal in the maintenance of gut immune homeostasis. Impaired barrier function due to altered cell to cell junctions, enables interactions between the microbiota and host immune responses prior to the onset of inflammation and epit...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 9621dfc8-518d-564c-90b2-8e71c6ce2aec
DOI: 10.25560/25735

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Studies of the aetiopathogenesis of pouchitisDOI 10.25560/25735Read

Cellular and molecular mechanisms in the pathogenesis of pouchitis: more than just the microbiota.Semantic proximity Read

Gene expression profiles of ileal inflammatory bowel disease correlate with disease phenotype and advance understanding of its immunopathogenesis.Semantic proximity Read

Dysbiosis in Pouchitis: Evidence of Unique Microfloral Patterns in Pouch InflammationSemantic proximity Read

Abnormal mucosal immune response to altered bacterial flora following restorative proctocolectomy in patients with ulcerative colitis: serologic measures, immunogenetics, and clinical correlations.Semantic proximity Read

Endoscopic Normalization and Transition of J-Pouch Phenotypes Over Time in Patients With Inflammatory Bowel Disease.Semantic proximity Read

Endoscopic Phenotype of the J Pouch in Patients With Inflammatory Bowel Disease: A New Classification for Pouch Outcomes.Semantic proximity Read

The Bacteriology of PouchitisSemantic proximity Read

Mucosal integrity and barrier function in the pathogenesis of early lesions in Crohn's disease.Semantic proximity Read

Histopathology of Colectomy Specimens Predicts Endoscopic Pouch Phenotype in Patients with Ulcerative Colitis.Semantic proximity Read

Distinct microbiome in pouchitis compared to healthy pouches in ulcerative colitis and familial adenomatous polyposisSemantic proximity Read

Nuclear Calprotectin mediates Epithelial Wound Healing Defects in Crohn’s Disease related FistulaSemantic proximity Read

Early Transcriptomic Changes in the Ileal Pouch Provide Insight into the Molecular Pathogenesis of Pouchitis and Ulcerative ColitisSemantic proximity Read