Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Human gut-specific homeostatic dendritic cells are generated from blood precursors by the gut microenvironment.

Inflammatory bowel diseases - 1 Jul 2012

Mann Elizabeth R, Bernardo David, Al-Hassi Hafid Omar, English Nicholas R, Clark Susan K, McCarthy Neil E, Milestone Andrew N, Cochrane Stella A, Hart Ailsa L, Stagg Andrew J, Knight Stella C

Abstract excerpt

BACKGROUND: Dendritic cells (DC) dictate not only the type of T-cell immunity, but also homing patterns of T cells in mice. In humans, we characterized normal human gut DC and tested whether gut-specific homeostatic DC could be generated from blood precursors by factors in the gut microenvironment. METHODS: We characterized the phenotype and function of healthy human gut DC compared with blood and skin DC, and...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Dendritic Cells
Share to Gastrointestinal Tract

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Microscopy, Fluorescence

Share to Receptors, Lymphocyte Homing

Share to T-Lymphocytes

Share to Transforming Growth Factor beta

Share to Tretinoin

Source

Identifiers

PMID: 21987473
DOI: 10.1002/ibd.21893

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Human gut-specific homeostatic dendritic cells are generated from blood precursors by the gut microenvironment.PMID 21987473Read ↗

PD-L1+ and XCR1+ dendritic cells are region-specific regulators of gut homeostasisSemantic proximity Read ↗

A novel esophageal tolerogenic dendritic cell subsetSemantic proximity Read ↗

Homeostatic IL-13 in healthy skin directs dendritic cell differentiation to promote TH2 and inhibit TH17 cell polarization.Semantic proximity Read ↗

The skin environment controls local dendritic cell differentiation and function through innate IL-13Semantic proximity Read ↗

The ontogenetic path of human dendritic cells.Semantic proximity Read ↗

Comparative phenotypic and functional analysis of migratory dendritic cell subsets from human oral mucosa and skin.Semantic proximity Read ↗

Retinoic acid regulates the development of a gut-homing precursor for intestinal dendritic cells.Semantic proximity Read ↗

Comparative analysis of human gut- and blood-derived mononuclear cells: contrasts in function and phenotype.Semantic proximity Read ↗

Langerin-expressing dendritic cells in human tissues are related to CD1c+ dendritic cells and distinct from Langerhans cells and CD141high XCR1+ dendritic cellsSemantic proximity Read ↗

Characterization of human DNGR-1+ BDCA3+ leukocytes as putative equivalents of mouse CD8alpha+ dendritic cells.Semantic proximity Read ↗

Langerin-expressing dendritic cells in gut-associated lymphoid tissues.Semantic proximity Read ↗

Dendritic cells derived from murine colonic mucosa have unique functional and phenotypic characteristics.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.