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Article

Regulation of the mucosal phenotype in dendritic cells by PPARγ: role of tissue microenvironment.

Journal of leukocyte biology - 1 Mar 2014

Tuna Halide, Avdiushko Rita G, Sindhava Vishal J, Wedlund Leia, Kaetzel Charlotte S, Kaplan Alan M, Bondada Subbarao, Cohen Donald A

Abstract excerpt

Mucosal DCs play a critical role in tissue homeostasis. Several stimuli can induce a mucosal phenotype; however, molecular pathways that regulate development of mucosal DC function are relatively unknown. This study sought to determine whether PPARγ contributes to the development of the "mucosal" phenotype in mouse DCs. Experiments demonstrated that PPARγ activation in BMDCs induced an immunosuppressive phenotype...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 24295831
DOI: 10.1189/jlb.0713408
PMCID: PMC3923081

Genes

CCR9

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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