Article

Subset-based method for cross-tissue transcriptome-wide association studies improves power and interpretability

2023-01-12

Abstract excerpt

Integrating results from genome-wide association studies (GWAS) and studies of molecular phenotypes like gene expressions, can improve our understanding of the biological functions of trait-associated variants, and can help prioritize candidate genes for downstream analysis. Using reference expression quantitative trait loci (eQTL) studies, several methods have been proposed to identify significant gene-trait asso...

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Literature Corpus work: 56805a5f-3f5b-5976-8efa-8cff251ab436
DOI: 10.1101/2023.01.11.23284454

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