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Telomeres and Cancer

16 Dec 2021

Abstract excerpt

Telomeres cap the ends of eukaryotic chromosomes and are indispensable chromatin structures for genome protection and replication. Telomere length maintenance has been attributed to several functional modulators, including telomerase, the shelterin complex, and the CST complex, synergizing with DNA replication, repair, and the RNA metabolism pathway components. As dysfunctional telomere maintenance and telomerase...

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PMID: 34947936
DOI: 10.3390/life11121405

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