Article

Single nucleus transcriptome of a “Super RV” shows increased insulin and angiogenesis signaling

2023-11-29

Abstract excerpt

<h4>ABSTRACT</h4> The right ventricle (RV) is one of the four pumping chambers of the heart, pumping blood to the lungs. In severe forms of congenital heart disease and pulmonary hypertension, the RV is made to pump into the systemic circulation. Such systemic RVs typically display early failure due to pressure overload. In rare cases a systemic RV persists into later decades of life – colloquially called a ‘Supe...

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Literature Corpus work: 564ab69d-70ae-5c2b-afcd-ac7981992818
DOI: 10.1101/2023.11.28.569092

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