Article

Cellular and Transcriptional Landscape of Human Hypoplastic Left Heart Syndrome

2025-05-29

Abstract excerpt

<title>Abstract</title> <p>Hypoplastic left heart syndrome (HLHS) is a congenital heart defect characterized by impaired development of the left ventricle, often managed through surgical palliation creating a single ventricle (SV). Failure of the anatomical right ventricle (RV) represents a common complication with high mortality. We used single-nucleus RNA sequencing to generate a map of the pediatric non-failin...

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Literature Corpus work: aa3309ad-189e-54ad-aa12-228cf0069e93
DOI: 10.21203/rs.3.rs-6689087/v1

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