Article

A common DNA deletion altering the 3’UTR of mdr1 is associated with reduced mefloquine susceptibility in P. vivax parasites from Cambodian patients

2025-09-01

Abstract excerpt

<title>Abstract</title> <p> Artemisinin-combination therapies (ACTs) are now recommended for the treatment of uncomplicated malaria caused by <italic>Plasmodium vivax</italic> , the parasite responsible for the majority of malaria infections outside of Africa. We analyzed the genome sequences of 206 <italic>P. vivax</italic> parasites collected from Cambodian malaria patients and showed that more than 80% of...

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Literature Corpus work: bd2606b8-9ff1-5666-82e4-024ad887f552
DOI: 10.21203/rs.3.rs-6889263/v1

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