Article

Wnt5a gain- and loss-of-function present distinctly in craniofacial bone

2025-07-22

Abstract excerpt

<h4>ABSTRACT</h4> <h4>Introduction</h4> Robinow syndrome has characteristic craniofacial and dental features and can be caused by gain- or loss-of-function variants in Wnt family member 5A ( WNT5A ) non-canonical signaling. The craniofacial and dental manifestation of Robinow syndrome is heterogenous, as is the effect of altered Wnt5a in animal models. The relationship between Wnt5a and craniofacial and denta...

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Literature Corpus work: 55f0e588-b96e-59b2-834c-9cb02126d655
DOI: 10.1101/2025.07.21.665966

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