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Article

Signaling Pathways in Craniofacial Development: Insights from Rare Skeletal Disorders.

Current topics in developmental biology - 1 Jan 2015

Neben Cynthia L, Merrill Amy E

Abstract excerpt

In the developing embryo, signaling pathways define how the mesenchymal precursors of bone form individual skeletal elements with the proper size, shape, orientation, and integration. Disruptions to these signaling processes lead to a large variety of congenital conditions categorized as skeletal dysplasias. While individually these skeletal disorders are rare, collectively they represent a significant cause of...

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PMID: 26589936
DOI: 10.1016/bs.ctdb.2015.09.005

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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