Article
The serine/threonine kinase MINK1 directly regulates the function of promigratory proteins
2021-09-03
Abstract excerpt
Upregulation of the developmental Wnt/planar cell polarity pathway is observed in many cancers and is associated with cancer development at early and late stages. We recently showed that PRICKLE1 and VANGL2, two core Wnt/PCP components, are overexpressed in triple negative breast cancer and associated with poor prognosis. PRICKLE1 is a cytoplasmic protein phosphorylated by the poorly described serine/threonine kin...
Topics
Open a Topic to create a Post that cites this publication.
Identifiers and source
- Literature Corpus work
- 55e1f825-0ef9-5ffe-b7a8-75d3ac55e5d7
- DOI
- 10.1101/2021.09.02.458712
