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Article

Kallikrein-related peptidase 5 induces miRNA-mediated anti-oncogenic pathways in breast cancer

24 Oct 2014

Abstract excerpt

Kallikrein-related peptidase 5 (KLK5) displays aberrant expression in cancer. Recently, we showed KLK5 reconstitution in breast cancer cell lines suppresses malignancy. Present study aims to investigate the functional KLK5 mediated miRNA network on breast cancer progression, molecular subtype and survival. 28 miRNAs were up-regulated and 62 miRNAs were down-regulated upon KLK5 expression. Extracellular matrix...

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PMID: 25593998
DOI: 10.18632/oncoscience.91

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