Sex-specific transcriptome similarity networks elucidate comorbidity relationships

Abstract excerpt

Humans present sex-driven biological differences. Consequently, the prevalence of analyzing specific diseases and comorbidities differs between the sexes, directly impacting patients’ management and treatment. Despite its relevance and the growing evidence of said differences across numerous diseases (with 4,370 PubMed results published within the past year), knowledge at the comorbidity level remains limited. In...

Topics

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• Comorbidity
• Computational Biology
• Datasets as Topic
• Drug Discovery
• Gene Expression
• Genotype
• Sequence Analysis, RNA
• Sex Factors

Identifiers and source

Literature Corpus work

55948de9-690c-528f-8b01-9323cc126288

DOI

10.1101/2025.01.22.634077