Article
Puerarin Alleviates Myocardial Ischemia-Reperfusion Injury by Enhancing FUNDC1-Mediated Mitophagy
2026-02-26
Abstract excerpt
<title>Abstract</title> <p> Background Myocardial ischemia‑reperfusion injury (MI/RI) is a major contributor to adverse outcomes in ischemic heart disease. Mitochondrial dysfunction plays a central role in MI/RI, and modulating mitophagy has shown potential in attenuating such injury. Nevertheless, whether puerarin influences mitophagy during MI/RI remains poorly understood. Methods An in vivo MI/RI model (I...
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Identifiers and source
- Literature Corpus work
- 17f43bbe-c7a1-5a3f-a841-389e6d72e3ec
- DOI
- 10.21203/rs.3.rs-8860711/v1
