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Article

Exosomes from mesenchymal stem cells overexpressing MIF enhance myocardial repair

20 Jan 2020

Abstract excerpt

Accumulating evidence has shown that mesenchymal stem cell (MSC)-derived exosomes (exo) mediate cardiac repair following myocardial infarction (MI). Macrophage migration inhibitory factor (MIF), a proinflammatory cytokine, plays a critical role in regulating cell homeostasis. This study aimed to investigate the cardioprotective effects of exo secreted from bone marrow-MSCs (BM-MSCs) overexpressing MIF in a rat...

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Share to Cardiac Structural Anomalies and Repair
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PMID: 31960418
DOI: 10.1002/jcp.29456

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