Article

Tanshinone ⅡA Enhances the Therapeutic Efficacy of Mesenchymal Stem Cells Derived Exosomes in Myocardial Ischemia/reperfusion Injury via Up-regulating miR-223-5p

2021-11-18

Abstract excerpt

<h4>Background: </h4> Myocardial ischemia-reperfusion (I/R) injury is a serious obstacle for patients with coronary heart disease to benefit from post-ischemic reflow. After myocardial I/R injury, CCR2 + -resident macrophages are rapidly activated and participate in the subsequent inflammatory response, whereas CCR2 - -resident macrophages play a major role in attenuating cardiac inflammation and promoting tissue...

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Literature Corpus work: 746ea091-a6b5-5856-949a-a379325ce813
DOI: 10.21203/rs.3.rs-1062444/v1

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