Article

Novel Murine models of Mania and Depression

2022-03-18

Abstract excerpt

Neuropathological mechanisms triggering manic syndrome or manic episodes in bipolar disorder remain poorly characterised, as the research progress is severely limited by the paucity of appropriate animal models. Here we developed a novel manic mice model by combining a series of chronic unpredictable rhythm disturbances (CURD), which include disruption of circadian rhythm, sleep deprivation, exposure to cone light...

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Literature Corpus work: 5532e6ff-6cbf-596b-a1a8-8ad7de3ad6f1
DOI: 10.1101/2022.03.16.484557

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