Article

The COPI coatomer regulates several steps of HDL metabolism

2025-08-26

Abstract excerpt

<h4>Background</h4> Reverse cholesterol transport by high density lipoproteins (HDL) is considered as an anti-atherogenic metabolic pathway. Hepatocytes determine the efficacy of this pathway by the production of apolipoprotein A-I (apoA-I) and its lipidation by ATP binding cassette transporter A1 (ABCA1), selective uptake of cholesterol via scavenger receptor BI (SR-BI) and uptake of entire HDL particles. The mo...

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Literature Corpus work: 5507e47b-d85d-5013-a9cd-1a5b05be9dea
DOI: 10.1101/2025.08.21.25332476

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