Article
COPI Coatomer Regulates Several Steps of HDL Metabolism.
Arteriosclerosis, thrombosis, and vascular biology - 1 Oct 2026
Panteloglou Grigorios, Zanoni Paolo, Law Christopher S, Woods Brian, Othman Alaa, Yalcinkaya Mustafa, Norrelykke Simon F, Rzepiela Andrzej J, Stoma Szymon, Stebler Michael, Kerksiek Anja, Visentin Michele, Smit Marieke, Wolters Justina Clarinda, Kakava Sofia, Potapenko Anton, Schlumpf Eveline, Radosavljevic Silvija, Häusler Stephanie, Futema Marta, Dalila Nawar, Tybjaerg-Hansen Anne, Humphries Steve E, Kuivenhoven Jan Albert, Sluis Bart van de, Lütjohann Dieter, Meier Roger, Robert Jérôme, Chou Janet, Geha Raif S, Shum Anthony K, Rohrer Lucia, von Eckardstein Arnold
Abstract excerpt
BACKGROUND: Reverse cholesterol transport by HDLs (high-density lipoproteins) is considered an antiatherogenic metabolic pathway. Hepatocytes are the main contributors to the efficacy of this pathway by the production of apoA-I (apolipoprotein A1) and its lipidation by ABCA1 (ATP-binding cassette transporter A1), selective uptake of cholesterol via SR-BI (scavenger receptor class B type 1), and uptake of entire...
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- Animals
- Humans
- ATP Binding Cassette Transporter 1