Article

Sparse Polygenic Risk Score Inference with the Spike-and-Slab LASSO

2025-01-29

Abstract excerpt

Large-scale biobanks, with comprehensive phenotypic and genomic data across hundreds of thousands of samples, provide ample opportunities to elucidate the genetics of complex traits and diseases. Consequently, there is a growing demand for robust and scalable methods for disease risk prediction from genotype data. Performing inference in this setting is challenging due to the high-dimensionality of genomic data, e...

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Literature Corpus work: 54c16ea6-7d26-5394-976a-191cf30924b6
DOI: 10.1101/2025.01.28.25321292

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