Article

Differential Role of Aldosterone and Transforming Growth Factor beta-1 in Cardiac Remodelling

2023-07-03

Abstract excerpt

(1) Background: Angiotensin II, a major culprit in cardiovascular disease, activates mediators that are also involved in pathological cardiac remodelling. We aimed at investigating the effects of two of them: aldosterone (Ald) and transforming growth factor-beta-1 (TGF-β1 ), on cardiac remodelling in an in vivo model. (2) Methods: Six-week-old male wild-type (WT) and TGF-β1 -overexpressing transgenic (TG...

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Literature Corpus work: 54b36c61-e16f-55f0-8d20-f5ce62480346
DOI: 10.20944/preprints202307.0042.v1

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