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QUENTIN: reconstruction of disease transmissions from viral quasispecies genomic data

15 Jun 2017

Abstract excerpt

Motivation: Genomic analysis has become one of the major tools for disease outbreak investigations. However, existing computational frameworks for inference of transmission history from viral genomic data often do not consider intra-host diversity of pathogens and heavily rely on additional epidemiological data, such as sampling times and exposure intervals. This impedes genomic analysis of outbreaks of highly...

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PMID: 29304222
DOI: 10.1093/bioinformatics/btx402

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