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Phylodynamics of Infectious Disease Epidemics

21 Sept 2009

Abstract excerpt

We present a formalism for unifying the inference of population size from genetic sequences and mathematical models of infectious disease in populations. Virus phylogenies have been used in many recent studies to infer properties of epidemics. These approaches rely on coalescent models that may not be appropriate for infectious diseases. We account for phylogenetic patterns of viruses in susceptible-infected...

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PMID: 19797047
DOI: 10.1534/genetics.109.106021

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