Article

Evolution of functional diversity in the holozoan tyrosine kinome

2021-08-04

Abstract excerpt

The emergence of multicellularity is strongly correlated with the expansion of tyrosine kinases, a conserved family of signaling enzymes that regulates pathways essential for cell-to-cell communication. Although tyrosine kinases have been classified from several model organisms, a molecular-level understanding of tyrosine kinase evolution across all holozoans is currently lacking. Using a hierarchical sequence con...

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Literature Corpus work: 54a11eb5-8dc7-5a16-b7a7-6a1a163214e0
DOI: 10.1101/2021.08.03.454916

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