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Genome-wide Association Study Meta-analysis of Neurofilament light (NfL) levels in blood reveals novel loci related to neurodegeneration

2022-12-14

Abstract excerpt

<h4>Background</h4> Neurofilament light chain (NfL) levels in circulation have been established as a sensitive biomarker of neuro-axonal damage across a range of neurodegenerative disorders. Elucidation of the genetic architecture of blood NfL levels and its genetic correlation with neurological traits could therefore provide new insights into shared molecular mechanisms underlying neurodegenerative disorders. <h4...

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Literature Corpus work
540dfc30-e6ca-50f6-9a02-852c3458f696
DOI
10.1101/2022.12.14.22283446
Open publication

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Genome-wide Association Study Meta-analysis of Neurofilament light (NfL) levels in blood reveals novel loci related to neurodegenerationDOI 10.1101/2022.12.14.22283446
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