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Article

Evidence of polygenic regulation of the physiological presence of neurofilament light chain in human serum

2022-10-07

Abstract excerpt

The measurement of neurofilament light chain (NfL) in blood is a promising biomarker of neurological injury and disease. We investigated the genetic factors that underlie serum NfL levels (sNfL) of individuals without neurological conditions. We performed a discovery genome-wide association study (GWAS) of sNfL in participants of the German BiDirect Study (N=1,899). A secondary GWAS for meta-analysis was performed...

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Literature Corpus work
d4b4e37b-d3f5-5eca-84f0-d94aea95720b
DOI
10.21203/rs.3.rs-422221/v1
Open publication

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Evidence of polygenic regulation of the physiological presence of neurofilament light chain in human serumDOI 10.21203/rs.3.rs-422221/v1
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