Article

<i>TMEM106B</i> and <i>CPOX</i> are genetic determinants of cerebrospinal fluid Alzheimer’s disease biomarker levels

2020-06-01

Abstract excerpt

<h4>Background</h4> Neurofilament light (NF-L), chitinase-3-like protein 1 (YKL-40), and neurogranin (Ng) are utilized as biomarkers for Alzheimer’s disease (AD), to monitor axonal damage, astroglial activation, and synaptic degeneration, respectively. Here we performed genome-wide association study (GWAS) analyses using all three biomarkers as outcome. <h4>Methods</h4> DNA and cerebrospinal fluid (CSF) samples...

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Literature Corpus work: 7b192b4d-546d-5634-bfb2-4c633cc5017f
DOI: 10.1101/2020.05.31.125633

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