Article

Kinetic networks identify Twist2 as a key regulatory node in adipogenesis

2021-11-19

Abstract excerpt

Adipocytes contribute to metabolic disorders such as obesity, diabetes, and atherosclerosis. Prior characterizations of the transcriptional network driving adipogenesis overlook transiently acting transcription factors (TFs), genes, and regulatory elements that are essential for proper differentiation. Moreover, traditional gene regulatory networks provide neither mechanistic details about individual RE-gene relat...

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Literature Corpus work: 53e5d148-8f5d-5150-857c-e3a117b7c154
DOI: 10.1101/2021.11.17.469040

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