Article

Engineered cartilage from human chondrocytes with homozygous knockout of cell cycle inhibitor p21

2019-08-09

Abstract excerpt

Risk factors for the development of osteoarthritis (OA) include genetic background and focal cartilage injury. The search for disease-modifying OA therapies would benefit from a more comprehensive knowledge of the genetic variants that contribute to chondrocyte dysfunction and the barriers to cartilage regeneration. One goal of this study was to establish a system for producing engineered cartilage tissue from gen...

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Literature Corpus work: 53dc3c60-d3db-5e4b-8459-8306d14d8fe3
DOI: 10.1101/731216

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