Article

The human ApoE4 variant reduces functional recovery and neuronal sprouting after incomplete spinal cord injury in male mice

2020-11-05

Abstract excerpt

Spinal cord injury (SCI) is a devastating form of neurotrauma. Patients who carry one or two ApoE4 alleles show worse functional outcomes and longer hospital stays after SCI but the cellular and molecular underpinnings for this genetic link remain poorly understood. Thus, there is a great need to generate animal models to accurately replicate the genetic determinants of outcomes after SCI to spur development of tr...

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Literature Corpus work: 53c29f96-f77d-5be1-8c3c-c4efafdef267
DOI: 10.1101/2020.11.05.369900

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