Article
Cystine addiction of triple-negative breast cancer associated with EMT augmented death signaling.
Oncogene - 27 Jul 2017
Tang X, Ding C-K, Wu J, Sjol J, Wardell S, Spasojevic I, George D, McDonnell D P, Hsu D S, Chang J T, Chi J-T
Abstract excerpt
Despite the advances in the diagnosis and treatment of breast cancer, breast cancers still cause significant mortality. For some patients, especially those with triple-negative breast cancer, current treatments continue to be limited and ineffective. Therefore, there remains an unmet need for a novel therapeutic approach. One potential strategy is to target the altered metabolic state that is rewired by oncogenic...
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