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Comprehensive assessments of germline deletion structural variants reveal the association between prognostic MUC4 and CEP72 deletions and immune response gene expression in colorectal cancer patients

2020-09-21

Abstract excerpt

<title>Abstract</title> <p><bold>Background </bold>Functional disruptions by large germline genomic structural variants in susceptible genes are known risks for cancer. Few studies have used deletion structural variants (DSVs) to predict cancer risk with neural networks or studied the relationship between DSVs and immune gene expression to stratify prognosis.<bold>Methods </bold>Whole-genome sequencing (WGS) data...

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Literature Corpus work
53836ef7-0ac5-5886-a526-369e6983264d
DOI
10.21203/rs.3.rs-79420/v1
Open publication

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