Article
The Clinical Relevance of Frequent Germline Genetic Variants Detected by Targeted Sequencing in Patients With Rectal Adenocarcinoma (READ).
Cancer genomics & proteomics - 1 Jan 2000
Huang Kevin Chih-Yang, Chiang Shu-Fen, Ke Tao-Wei, Chen William Tzu-Liang, Chen Tsung-Wei, Chao Kun-San Clifford
Abstract excerpt
BACKGROUND: The progression of colorectal cancer (CRC) mainly stems from the occurrence of somatic mutation. However, there is little information that can be used to comprehensively analyse the importance of germline variants in CRC patients. PATIENTS AND METHODS: The candidate germline variants between tumor relapse and cured rectal adenocarcinoma (READ) were firstly filtered by whole-exome sequencing (n=4), and...
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