Article

Targeted amplicon deep sequencing of ama1 and mdr1 to track within-host P. falciparum diversity throughout treatment in a clinical drug trial

2024-03-14

Abstract excerpt

<h4>Introduction: </h4> Antimalarial therapeutic efficacy studies are routinely conducted in malaria-endemic countries to assess the effectiveness of antimalarial treatment strategies. Targeted amplicon sequencing (AmpSeq) uniquely identifies and quantifies genetically distinct parasites within an infection. In this study, AmpSeq of Plasmodium falciparum apical membrane antigen 1 ( ama1 ), and multidrug resistance...

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Literature Corpus work: 53785c5b-cd36-5a84-bcae-56a10d6f63a9
DOI: 10.12688/wellcomeopenres.17736.4

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