Back to search

Article

Spatio-temporal distribution of antimalarial drug resistant gene mutations in a Plasmodium falciparum parasite population from Kilifi, Kenya: A 25-year retrospective study

2022-02-08

Abstract excerpt

<ns7:p> <ns7:bold>Background:</ns7:bold> Antimalarial drug resistance is a major obstacle to sustainable malaria control. Here we use amplicon sequencing to describe molecular markers of drug resistance in <ns7:italic>Plasmodium falciparum</ns7:italic> parasites from Kilifi county in the coastal region of Kenya over a 25-year period. </ns7:p> <ns7:p> <ns7:bold>Methods:</ns7:bold> We performed <ns7:italic>P. falcip...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work
8a570ac2-e306-5ca7-8cd5-b7751e0e4eab
DOI
10.12688/wellcomeopenres.17656.1
Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest
Interactive article relationship graphSelect a related publication card to move it into the centre and load its closest explainable connections. Solid lines are source-backed structured connections. Dashed lines are semantic discovery signals and are not scientific evidence.
Spatio-temporal distribution of antimalarial drug resistant gene mutations in a Plasmodium falciparum parasite population from Kilifi, Kenya: A 25-year retrospective studyDOI 10.12688/wellcomeopenres.17656.1
Spatial Surveillance of Plasmodium falciparum Kelch 13 Mutations Reveals Emerging Artemisinin Resistance in KenyaSemantic proximity
Longitudinal surveillance of kelch13 identifies C469Y, P553L, R561H and A675V mutations associated with artemisinin resistance in Western KenyaSemantic proximity
Emergence and Spread of Plasmodium falciparum Kelch 13 Mutations in Selected Counties of Kenya: Implications for Responding to Artemisinin Partial Resistance.Semantic proximity
Evolving patterns of antimalarial drug resistance markers in symptomatic infections in Kenya, 2013-2022.Semantic proximity
Comprehensive Spatiotemporal Analysis of Antimalarial Drug Resistance Markers in Mali: A Genomic Surveillance ApproachSemantic proximity
Molecular Surveillance of malaria in Nigeria reveals expansion of chloroquine-sensitive infectionsSemantic proximity
Impacts of Antimalarial Drugs on Plasmodium falciparum Drug Resistance Markers, Western Kenya, 2003-2015.Semantic proximity
Surveillance of molecular markers of antimalarial drug resistance in Plasmodium falciparum and Plasmodium vivax in Federally Administered Tribal Area (FATA), Pakistan.Semantic proximity
Temporal trends in molecular markers of drug resistance in Plasmodium falciparum in human blood and profiles of corresponding resistant markers in mosquito oocysts in Asembo, western KenyaSemantic proximity
Temporal trends in prevalence of Plasmodium falciparum drug resistance alleles over two decades of changing antimalarial policy in coastal KenyaSemantic proximity
Genomic Surveillance of malaria reveals localized sporadic emergence of artemisinin partial resistance and wide-spread sulfadoxine-pyrimethamine resistance in GhanaSemantic proximity
Molecular Markers of Antimalarial Resistance in Children with Uncomplicated Plasmodium falciparum at Two Sites in Liberia in 2022-2023Semantic proximity
Select a neighboring publication to make it the new centre.