Article
Genetic Diversity of Plasmodium falciparum and Distribution of Antimalarial Drug Resistance Mutations in Symptomatic and Asymptomatic Infections.
Antimicrobial agents and chemotherapy - 16 Aug 2022
Sarah-Matio Elangwe M, Guillochon Emilie, Nsango Sandrine E, Abate Luc, Ngou Christelle M, Bouopda Gaelle A, Feufack-Donfack Lionel B, Bayibéki Albert N, Tchioffo Tsapi Majoline, Talman Arthur, Marin-Menendez Alejandro, Ayong Lawrence, Claessens Antoine, Lefèvre Thierry, Berry Antoine, Morlais Isabelle
Abstract excerpt
Malaria control relies on passive case detection, and this strategy fails detecting asymptomatic infections. In addition, infections in endemic areas harbor multiple parasite genotypes that could affect case management and malaria epidemiology. Here, we performed AmpSeq genotyping to capture polymorphisms associated with antimalarial resistance and the genetic diversity within natural Plasmodium falciparum...
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