Article

A high-throughput 3D cantilever array to model airway smooth muscle hypercontractility in asthma

2022-10-27

Abstract excerpt

Asthma is often characterized by tissue-level mechanical phenotypes that include remodeling of the airway and an increase in airway tightening driven by the underlying smooth muscle. Existing therapies only provide symptom relief and do not improve the baseline narrowing of the airway or halt progression of the disease. To investigate such targeted therapeutics, there is a need for models that can recapitulate the...

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Literature Corpus work: 535bf28e-c36f-5cf1-8f73-b8ca5c08205d
DOI: 10.1101/2022.10.25.513767

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