Article

Predicting cognitive and mental health traits and their polygenic architecture using large-scale brain connectomics

2019-04-16

Abstract excerpt

Cognitive abilities and mental disorders are complex traits sharing a largely unknown neuronal basis and aetiology. Their genetic architectures are highly polygenic and overlapping, which is supported by heterogeneous phenotypic expression and substantial clinical overlap. Brain network analysis provides a non-invasive means of dissecting biological heterogeneity yet its sensitivity, specificity and validity in cl...

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Literature Corpus work: 532989d7-a358-5352-9723-85f88c3ca1e2
DOI: 10.1101/609586

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